HPS3 anticorps (C-Term)

N° du produit ABIN374450

L’anticorps Chèvre Polyclonal anti-HPS3 a été validé pour WB. Il convient pour détecter HPS3 dans des échantillons de Humain.

Aperçu rapide pour HPS3 anticorps (C-Term) (ABIN374450)

Antigène: HPS3 (Hermansky-Pudlak Syndrome 3 (HPS3))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp HPS3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HPS3 anticorps

Épitope: C-Term

Séquence: PYLLYCSRKK PLT

Specificité: This antibody recognizes HPS3/Cocoa

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide from the C Terminus of the protein sequence according to NP_115759

Information d'application

Indications d'application: Peptide ELISA: > 1/32,000. Western Blot: 1-3 μg/mL. Detects a band of Approx 110 kDa in A431 cell lysate(Predicted Molecular Weight: 114 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur HPS3

Antigène: HPS3 (Hermansky-Pudlak Syndrome 3 (HPS3))

Autre désignation: HPS3

Sujet: HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.Synonyms: Hermansky-Pudlak syndrome 3

ID gène: 84343

NCBI Accession: NP_115759

UniProt: Q969F9